FIG 5.

Effect of aroG silencing on M. tuberculosis in supplemented media. (A, C, E). M. tuberculosis growth curves and dilution spots in the presence or absence of Atc 100 ng/mL with aa supplement. (B, D, F) M. tuberculosis growth curves and dilution spots in the presence or absence of Atc 100 ng/mL with the aromix supplement. Cultures were inoculated to a starting A₆₀₀ of 0.07. Data are the mean ± standard deviation from biological and technical duplicates. Statistical analysis was performed using two-way ANOVA analysis followed by Bonferroni’s posttest. *, P < 0.03; **, P < 0.002; ***, P < 0.001.