FIG 8.

Role of antioxidant in the synergistic killing of SCF with nitrite. (A) Genes with antioxidant functions present in P. aeruginosa and the catalyzed reactions of the encoded enzymes. (B) Expression of genes encoding major classes of antioxidants in the presence of nitrite (20 mM). (C and D) Catalase (CAT) activity (C) and SOD activity (D) in the presence of exogenous nitrite (20 mM). Results are displayed as mean ± SEM of three (C and D) or four (B) biological replicas, and significant differences are identified (*, P < 0.05; **, P < 0.01) as determined by two-tailed Student's t test.