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. 2022 Jul 11;10(4):e00794-22. doi: 10.1128/spectrum.00794-22

FIG 4.

FIG 4

Combination of BEZ235 and Lactobacillus rhamnosus HN001-attenuated allograft rejection. (A) Survival of the cardiac allografts in mice. (B) Cardiac allografts were harvested on day 7 after transplantation, and the tissue sections were stained with hematoxylin and eosin (×100 or ×400). (C) Serum proinflammatory cytokine levels. (D) IL-6, IL-17, MCP-1, and IFN-γ staining of grafts from the BEZ235 treatment group and control group mice at day 7 after heart transplantation (×400 original magnification). Data are shown as the mean ± SEM (ns, P ≥ 0.05; *, P < 0.05; **, P < 0.01).