TABLE 2.
MIC values (n = 3) in μM (in μg/mL) for C16-Im-KTTKS and KTTK(C16Im)S against MDR clinical isolates of Gram-positive and Gram-negative bacteria
| MDR | Peptide |
Ciprofloxacin | |
|---|---|---|---|
| C16Im-KTTKS | KTTK(C16Im)S | ||
| KP010 | 37.9 (37.0) | 21.7 (20.0) | 48.0 (16.0) |
| PA004 | 18.9 (18.5) | 96.0 (32.0) | |
| SA007 | 18.9 (18.5)a | 193.0 (64.0) | |
The MBC was 2× the MIC; In all other cases the MBC was equal to the MIC.