TABLE 3.
Factors associated with the growth index of HIV-1 transmission clusters using stepwise modelsa
| Characteristics | Cluster growth ≥ 1.57 |
Cluster growth ≥ 5.28 |
||
|---|---|---|---|---|
| OR (95% CI) | P | OR (95% CI) | P | |
| Gender | ||||
| Male | ref | ref | ||
| Female | 0.277 (0.152, 0.503) | <0.001 | 0.083 (0.019, 0.361) | 0.001 |
| Age group | ||||
| Below 20 | 1.223 (0.743, 2.012) | 0.428 | ||
| 21~30 | ref | |||
| 31~40 | 0.942 (0.729, 1.216) | 0.644 | ||
| 41~ | 0.600 (0.436, 0.826) | 0.002 | ||
| Education level | ||||
| Primary or below | ref | |||
| Junior or high | 1.103 (0.600, 2.026) | 0.753 | ||
| College or others | 1.145 (0.605, 2.168) | 0.677 | ||
| Not disclosed | 0.178 (0.057, 0.552) | 0.003 | ||
| Occupation | ||||
| Unskilled work | ref | |||
| Skilled/professional work | 1.664 (1.122, 2.470) | 0.011 | ||
| Students | 1.104 (0.675, 1.807) | 0.693 | ||
| Unemployment | 0.896 (0.632, 1.270) | 0.538 | ||
| Not disclosed | 1.051 (0.804, 1.374) | 0.717 | ||
| Infection routes | ||||
| MSM | ref | ref | ||
| HET | 0.329 (0.234, 0.463) | <0.001 | 0.188 (0.121, 0.294) | <0.001 |
| PWID | 0.043 (0.027, 0.069) | <0.001 | 0.023 (0.012, 0.046) | <0.001 |
| Genotypes | ||||
| B | 0.074 (0.027, 0.203) | <0.001 | ||
| CRF01_AE | ref | |||
| CRF07_BC | 14.015 (11.092, 17.710) | <0.001 | ref | |
| CRF55_01B | 41.220 (27.002, 62.925) | <0.001 | 0.014 (0.008, 0.025) | <0.001 |
a
The factors were removed from the multivariate model if P > 0.1, using stepwise progress. HET, heterosexually transmitted; MSM, men who have sex with men; PWID, people who inject drugs.