TABLE 2.
Metadata, subspecies, genotypic resistance, and clustering with DCCs of included M. abscessus isolates from German sites
| CF |
Non-CF |
||||
|---|---|---|---|---|---|
| Isolate characteristics | Patients [n] |
Isolates [n] |
Patients [n] |
Isolates [n] |
P valuea |
| Total | 123 | 154 | 14 | 14 | |
| Material | |||||
| Sputum | 104 | 129 | 5 | 5 | <0.001 |
| Oropharyngeal swab | 11 | 13 | 0 | 0 | 0.60 |
| Bronchoalveolar lavage | 5 | 9 | 4 | 4 | <0.01 |
| Bronchial secretion | 3 | 3 | 2 | 2 | 0.081 |
| Soft tissue | 0 | 0 | 3 | 3 | <0.001 |
| Isolate type | |||||
| Primary isolates | 123 | 123 | 14 | 14 | |
| Sequential isolates | 17 | 31 | 0 | 0 | |
| Subspecies | |||||
| mabs | 83 | 107 | 6 | 6 | 0.081 |
| mmas | 35 | 42 | 5 | 5 | 0.55 |
| mbol | 5 | 5 | 3 | 3 | <0.05 |
| Genotypic antibiotic resistance | |||||
| Functional erm(41) | 78 | 102 | 7 | 7 | 0.39 |
| rrl mutation | 15 | 17 | 1 | 1 | 1 |
| rrs mutation | 5 | 5 | 0 | 0 | 1 |
| Clusters | |||||
| Absc 1 | 23 | 29 | 3 | 3 | 0.73 |
| Absc 2 | 15 | 21 | 0 | 0 | 0.36 |
| Mass 1 | 7 | 10 | 0 | 0 | 1 |
| Boll 1 | 0 | 0 | 1 | 1 | 0.10 |
| Unclustered | 30 | 30 | 6 | 6 | 0.20 |
a
Bold values denote statistical significance with a P value < 0.05.