TABLE 2.

Physical characteristics of E. anophelis C08 OMVs under different antibiotic conditions

Antibiotica	Protein concn (μg/mL)	OMV concn (particles/mL)	CFU/mL	No. of particles/CFU	Mean particle size (nm) ± SD	Mean particle zeta potential (mV) ± SD
Control	10.78	7.66 × 109	7.6 × 109	1.01	117.1 ± 4.5	−138.9 ± 202.5
Amikacin	44.19	8.43 × 109	7.15 × 109	1.18	127.5 ± 2.3	−82.6 ± 48.5
Ampicillin	9.26	5.93 × 109	6.2 × 109	0.96	129.5 ± 7.3	−37.5 ± 33.6
Chloramphenicol	62.41	9.96 × 1010	8.6 × 108	115.81	144.0 ± 1.8	−29.1 ± 29.8
Colistin	25.97	3.30 × 109	6.0 × 109	0.55	129.6 ± 1.2	−16.7 ± 18.1
Imipenem	52.09	1.50 × 1012	2.12 × 1010	70.84	119.5 ± 0.4	−18.4 ± 16.8
Meropenem	22.93	2.18 × 1010	5.05 × 109	4.32	139.3 ± 1.9	−9.6 ± 16.5
Minocycline	20.39	1.01 × 1011	3.1 × 108	322.58	181.5 ± 0.9	−9.0 ± 58.2
Tigecycline	16.44	6.97 × 1010	1.42 × 1010	4.91	144.7 ± 0.1	−22.5 ± 17.3

^aOne-half the MICs were used for the following antibiotics: amikacin (16 μg/mL), ampicillin (32 μg/mL), chloramphenicol (32 μg/mL), colistin (2 μg/mL), imipenem (4 μg/mL), meropenem (4 μg/mL), minocycline (1 μg/mL), and tigecycline (4 μg/mL).