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. 2022 Aug 9;10(4):e02006-22. doi: 10.1128/spectrum.02006-22

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Copyright © 2022 Leuzinger et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license.

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FIG 1 — Comparison of the cumulated sensitivity for Omicron detection with the Roche-SARS-CoV-2 and the Acon-FlowFlex-SARS-CoV-2 rapid antigen tests. Cumulative sensitivity of the Roche-SARS-CoV-2 and the Acon-FlowFlex-SARS-CoV-2 RATs for Omicron BA.1 detection were compared in Ct-matched UTM samples with early-pandemic SCoV2 variants (B.1.160 and B.1.177; n = 92) (1), Omicron BA.2 and Omicron BA.5 (n = 100). SCoV2 loads were determined using the cobas SARS-CoV-2 test on the cobas6800 platform (Roche). A. Cumulated sensitivity of the Roche-SARS-CoV-2 (BA.1) and the Roche-SARS-CoV-2(B.1.160 and B.1.177) (n = 92; median, 25th and 75th percentile; Mann-Whitney-U test). B. Cumulated sensitivity of the Roche-SARS-CoV-2-Antigen (BA.1) and the Acon-FlowFlex-SARS-CoV-2 (BA.1) (n = 92; median, 25th and 75th percentile; Mann-Whitney-U test). C. Cumulated sensitivity of the Roche-SARS-CoV-2 and the Acon-FlowFlex-SARS-CoV-2 for Omicron BA.1, Omicron BA.2 and Omicron BA.5 (n = 100; median, 25th and 75th percentile; Mann-Whitney-U test). D. Receiver operating characteristic analysis (ROC) curves for the Roche-SARS-CoV-2 and the Acon-FlowFlex-SARS-CoV-2 for the different SCoV2 variants stratified by SCoV2 RNA loads.