TABLE 4.

Association between α-, β-, and γ-HPV infections and HNSCC

HPV positivity	Crude OR (95% CI)	P value	Adjusted ORa (95% CI)	P valueb
Any α-HPV
HPV−	1		1
HPV+	0.4 (0.1 to 1.2)	0.112	0.40 (0.1 to 1.2)	0.111
Any β-HPV
HPV−	1		1
HPV+	1.2 (0.9 to 1.7)	0.179	1.18 (0.9 to 1.6)	0.299
Types associated with disease
HPV100	2.6 (0.9 to 7.8)	0.079	2.75 (0.9 to 8.2)	0.070
HPV111	0.5 (0.2 to 1.1)	0.089	0.5 (0.2 to 1.2)	0.116
HPV124	0.6 (0.3 to 1.1)	0.081	0.5 (0.3 to 1.0)	0.061
HPV174	3.4 (0.98 to 11.4)	0.053	3.1 (0.9 to 10.6)	0.073
Any γ-HPV
HPV−	1		1
HPV+	1.1 (0.8 to 1.5)	0.688	1.0 (0.7 to 1.5)	0.830
Types associated with disease
HPV95	zero HPV95 in controls	-c	-	-
HPV123	zero HPV95 in controls	-	-	-
HPV134	0.4 (0.2 to 0.96)	0.042	0.42 (0.2 to 0.96)	0.041
HPV168	0.19 (0.0 to 0.99)	0.049	0.18 (0.0 to 0.98)	0.048

^aORs were adjusted for age (10-year intervals), gender, place of residence, tobacco use, opium use, and socioeconomic status.

^bItalic p values indicate positive trends. Bold p values indicate a significant association.

^cDue to zero number, it was not possible to estimate ORs and 95% CIs.