FIG 4.
Correlation between the genetic diversity of the replication-competent reservoir and specific features of treatment histories. (A) Correlation between the diversity of the replication-competent reservoir (expressed by the MPD) and the delay before controlled viremia (P = 0.0194, r = 0.864). (B) No correlation was observed between the diversity of the replication-competent reservoir and the duration of a suppressive treatment (P = 0.3571, r = −0.414). (C) Correlation between the frequency of clonal sequences within the replication-competent reservoir and the duration of a suppressive treatment (P = 0.0190, r = 0.822). (D) Correlation between the difference of infectivity for isolates from each patient and the time before reaching controlled viremia (P = 0.0254, r = 0.790). Spearman test.
