The representative cytocochleograms presented correlate with the histological findings. A) Low Dose OR-404IT (0.5 mg ciprofloxacin + 0.2 mg dexamethasone), B) High Dose OR-404IT (1.5 mg ciprofloxacin + 0.6 mg dexamethasone), C) Vehicle (2.1 mg inactive excipients), and D) Saline (negative control), via the transtympanic route did not cause mortality and did not affect cytocochleograms. As expected, E) Positive Toxicity Control (10% neomycin) displayed significant loss of outer and inner hair cells.