Table 6. Other non-invasive biomarkers.
Author, year | Population | Study | Biomarkers | Outcome |
Leung et al, 2013 (48) | 11Children and adults | Prospective study | FeNO | No supporting role for FeNO determination in the management of EoE |
Lanz et al, 2012 (49) | 55Children and adolescents | Case-control study | FeNO | Measurement of FeNO does not help identify EoE from GERD |
Moye et al, 2019 (50) | 24Children and adolescents | Prospectivecase-controlstudy | Plasmametabolomicsprofile | Notable candidate biomarkers include dimethylarginine, putrescine, and N-acetylputrescine |
Cunnion et al, 2016 (51) | 75Children and adults | Case-control study | Urinary 3-BT | Median normalized 3-BT levels were increased 93-fold in patients with EoE compared to controls |
BT, bromotyrosine; FeNO, Fractionated exhaled nitric oxide; GERD, gastroesophageal reflux disease.