Skip to main content
. 2019 Aug 27;96(4):406–408. doi: 10.1016/j.jped.2019.08.001

Table 1.

Studies on sarcopenia in pediatric patients with chronic liver disease.

Author/Year Patients/number/gender Age Method of diagnosis Evaluation Clinical outcome
Mangus 201714 ESLD/35/ females 60%
Age- and sex-matched healthy controls/35.
Mean 7.8 (range 0•17) yrs. CT L 2-L3
Psoas muscle area/height.
No assessment of muscle function.
Comparison with matched controls. 23% sarcopenia in ESLD vs. controls. Female gender: more fat and less muscle.
Age 13•17 yrs, higher prevalence of sarcopenia.
Lurz 201815 ESLD/23/ females 60%
Age- and sex-matched healthy controls/46
Mean 0.9 (range 0.5•3.7) yrs. CT L 3-L4
Psoas muscle area/height.
No assessment of muscle function.
Comparison with matched controls. Psoas muscle area significantly decreased in ESLD children.
Mager 201816 1•8 yrs
Post-liver transplantation/41/ females 58%.
0.5•17 years DEXA
No assessment of muscle function.
Skeletal muscle mass z-score < 2. Sarcopenia in 40% of post liver transplant children.

ESLD, end-stage liver disease., CT, computed tomography, DEXA, dual-energy X-Ray absorptiometry.