Table 3.
Maternal genotype correlation with obstetric outcomes and anthropometric parameters.
| Characteristica | Genotype |
||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
GCK rs1799884 |
p-valued |
TCF7L2 rs7903146 |
p-valued |
LEPR rs1137101 |
p-valued | Totala | |||||||
| GG | GA | AA | CC | CT | TT | AA | AG | GG | |||||
| Birth Weight (g) – n (%) - | |||||||||||||
| Low (<2,500) | 6(3.57) | 4(5.41) | 1(12.50) | 7(5.19) | 3(3.09) | 1(5.56) | 2(2.63) | 3(2.59) | 6(10.34) | 11(4.40) | |||
| Insufficient (2,500 to 2,999) | 31(18.45) | 15(20.27) | 3(37.50) | 28(20.74) | 18(18.56) | 3(16.67) | 15(19.74) | 24(20.69) | 10(17.24) | 49(19.60) | |||
| Adequate (3,000 to 3,999) | 120(71.43) | 47(63.51) | 4(50.00) | 92(68.15) | 66(68.04) | 13(72.22) | 52(68.42) | 81(69.83) | 38(65.52) | 171(68.40) | |||
| Excessive (≥4,000) | 11(6.55) | 8(10.81) | 0 | 8(5.93) | 10(10.31) | 1(5.56) | 7(9.21) | 8(6.90) | 4(6.90) | 19(7.60) | |||
| Mean (SD) | 3,332(462) | 3,325(555) | 3,148(596) | 0.134 | 3,297(479) | 3,363(511) | 3,314(524) | 0.750 | 3,387(537) | 3,309(465) | 3,270(492) | 0.386 | 3,324(494.60) |
| Gestational age (weeks) – n (%) - | |||||||||||||
| Preterm (<37) | 20(11.90) | 12(16.22) | 1(12.50) | 19(14.07) | 10(10.31) | 4(22.22) | 7(9.21) | 17(14.66) | 9(15.52) | 33(13.20) | |||
| Term (37 to <42) | 141(83.93) | 61(82.43) | 6(75.00) | 112(82.96) | 82(84.54) | 14(77.78) | 68(89.47) | 94(81.03) | 46(79.31) | 208(83.20) | |||
| Post-term (≥42) | 7(4.17) | 1(1.35) | 1(12.50) | 4(2.96) | 5(5.15) | 0 | 1(1.32) | 5(4.31) | 3(5.17) | 9(3.60) | |||
| Mean (SD) | 38.64(1.89) | 38.47(2.13) | 38.75(1.75) | 0.443 | 38.58(2.04) | 38.65(1.90) | 38.33(1.53) | 0.302 | 38.80e(1.60) | 38.39f(2.08) | 38.72e(2.09) | 0.037 | 38.59(1.96) |
| Sex of the baby – n female (%) | 86(51.19) | 46(62.16) | 2(25.00) | 0.074 | 72(53.33) | 51(52.58) | 11(61.11) | 0.797 | 39(51.32) | 59(50.86) | 36(62.07) | 0.336 | 134(53.60) |
| Pre-pregnancy BMI (kg/m2) - mean (SD) | 24.47(4.89) | 23.49(4.86) | 24.17(5.24) | 0.964 | 23.95(5.15) | 24.14(4.42) | 25.97(5.24) | 0.264 | 23.95(4.39) | 24.74(5.28) | 23.32(4.62) | 0.184 | 24.17(4.90) |
| Total n (%)b | 168(67.20) | 74(29.60) | 8(3.20) | 135(54.00) | 97(38.80) | 18(7.20) | 76(30.40) | 116(46.40) | 58(23.20) | N = 250c(100) | |||
a
Data are expressed as number of subjects in a group (%) or mean (Standard deviation - SD).
b
n, number of subjects for a specific characteristic.
c
N, total number of subjects examined.
d
Pearson's chi-square test was used to categorical variables and One Way ANOVA was used to variables in continuous form.
e,f Averages followed by same letter did not have statistical differences in Bonferroni test.