Table 2.
Information on the hospitalization period in the neonatal intensive care unit – postnatal factors of newborns with congenital diaphragmatic hernia according to the occurrence of death.
| n = 121 (%) | Death n = 71 (%) | Survival n = 50 (%) | OR (95% CI) | p-Value | |
|---|---|---|---|---|---|
| Transient tachypnea of the NB | 3 (2.5) | 1 (1.4) | 2 (4.0) | 0.541 (0.106–2.697) | 0.337 |
| Hyaline membrane disease | 11 (9.1) | 6 (8.4) | 5 (10.0) | 0.891 (0.510–1.558) | 0.449 |
| Pulmonary hypoplasia | 93 (76.8) | 69 (97.2) | 24 (48.0) | 3.074 (1.595–5.925) | 0.000 |
| Suspected sepsis | 74 (61.2) | 42 (59.1) | 32 (64.0) | 0.844 (0.643–1.106) | 0.152 |
| Confirmed sepsis | 9 (7.4) | 2 (2.8) | 7 (14.0) | 0.346 (0.101–1.184) | 0.017 |
| Bronchopulmonary Dysplasia | 4 (3.3) | 1 (1.4) | 3 (6.0) | 0.165 (0.073–2.210) | 0.403 |
| PDA | 87 (71.9) | 52 (73.2) | 35 (70.0) | 1.195 (0.804–1.778) | 0.396 |
| Preoperative vasoactive drugs | 91 (75.2) | 69 (97.2) | 22 (44.0) | 2.881 (1.671–4.967) | 0.000 |
| Postoperative vasoactive drugs | 49 (40.5) | 23 (32.4) | 26 (52.0) | 0.671 (0.482–0.933) | 0.015 |
| Preoperative transfusion | 22 (18.2) | 14 (19.7) | 8 (16.0) | 1.048 (0.738–1.488) | 1.000 |
| Postoperative transfusion | 30 (24.8) | 12 (16.9) | 18 (36.0) | 0.591 (0.374–0.935) | 0.010 |
| Nitric oxide | 66 (54.5) | 51 (71.8) | 15 (30.0) | 1.739 (1.281–2.360) | 0.000 |
| Sildenafil | 13 (10.7) | 8 (11.3) | 5 (10.0) | 1.005 (0.639–1.582) | 1.000 |
| Gastroesophageal reflux | 5 (4.1) | 0 (0) | 5 (10.0) | 2.758 (2.182–3.479) | 0.008 |
| GTT | 10 (8.3) | 2 (2.8) | 8 (16.0) | 0.309 (0.089–1.075) | 0.013 |
| Nissen | 9 (7.4) | 2 (2.8) | 7 (14.0) | 0.346 (0.101–1.184) | 0.027 |
| Arterial umbilical catheter | 86 (71.1) | 56 (78.9) | 30 (60.0) | 1.217 (0.885–1.674) | 0.251 |
| Venous umbilical catheter | 105 (86.8) | 68 (95.8) | 37 (74.0) | 1.413 (0.894–2.232) | 0.106 |
| PICC | 67 (55.4) | 19 (26.8) | 48 (96.0) | 0.293 (0.200–0.430) | 0.000 |
| Surgical repair | 77 (63.6) | 27 (38.0) | 50 (100) | 0.351 (0.259–0.475) | 0.000 |
| Use of mesh | 46 (38.0) | 18 (25.3) | 28 (56.0) | 1.011 (0.517–1.789) | 1.000 |
| Surgical complications | 6 (4.9) | 4 (5.6) | 2 (4.0) | 1.872 (0.983–3.565) | 0.194 |
| Liver herniation | 48 (39.7) | 30 (42.2) | 18 (36.0) | 1.033 (0.780–1.368) | 0.854 |
| Stomach herniation | 78 (64.5) | 48 (67.6) | 30 (60.0) | 1.012 (0.764–1.342) | 1.000 |
| Intestine herniation | 95 (78.5) | 50 (70.4) | 45 (90.0) | 0.615 (0.487–0.782) | 0.001 |
| Reoperation | 7 (5.8) | 3 (4.2) | 4 (8.0) | 0.688 (0.289–1.636) | 0.429 |
| Use of mesh in the reoperation | 4 (3.3) | 1 (1.4) | 3 (6.0) | 0.500 (0.077–3.265) | 0.571 |
n, number of patients; Student's t-test; 95% CI, 95% confidence interval; OR, odds ratio; NB, newborns; PDA, patent ductus arteriosus; GTT, gastrostomy; PICC, peripherally-inserted central venous catheter.