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. Author manuscript; available in PMC: 2023 Jul 15.
Published in final edited form as: J Immunol. 2022 Jul 6;209(2):262–269. doi: 10.4049/jimmunol.2000726

Figure 2. Inhibition of C3a signaling blocks Af induced suppression of 1α-hydroxylase and 25(OH)D3 to 1,25(OH)2D3 metabolism.

Figure 2.

A) Control HSNEC 1α-hydroxylase and B) 25(OH)D3 to 1,25(OH)2D3 metabolism is protected from Af induced suppression by C3a receptor antagonist (C3aRA) treatment. C3aR expression was not impacted by Af or 1,25(OH)2D3 treatment as determined by flow cytometry C) and western blotting D).