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. Author manuscript; available in PMC: 2023 Jul 15.
Published in final edited form as: J Immunol. 2022 Jul 6;209(2):262–269. doi: 10.4049/jimmunol.2000726

Figure 6: Inhibition of C3a signaling restores CRSwNP patient derived-HSNEC ability to metabolize 25(OH)D3 to 1,25(OH)2D3.

Figure 6:

Single cell suspensions of sinonasal tissues were examined for 1α-hydroxylase and either A) C3 or B) C3a. C) 25(OH)D3 metabolism in CRSwNP samples is restored to levels similar to control-subject derived cells with C3aRA.