Table 3.

Reduction in blood pressure of sacubitril-valsartan compared with other agents.

Intervention (drug, mg/day)	Control (drug, mg/day)	Reduction in BP (mmHg)	Range	P value
Sac-Val, 400	Val, 320	−5.97	−6.38, −5.56	<0.01
Sac-Val, 400	Olme, 40	−6.19	−12.38, −0.01	0.05
Sac-Val, 400	Olme, 20	−5.25	−8.64, −1.86	<0.01
Sac-Val, 400	Placebo	−13.99	−15.74, −12.24	<0.01
Sac-Val, 200	Olme, 20	−4.53	−6.54, −2.52	<0.01
Sac-Val, 200	Placebo	−12.57	−12.94, −12.20	<0.01
Sac-Val, 100	Placebo	−11.86	−12.22, −11.50	<0.01

Sac- Val, sacubitril-valsartan; Val, valsartan; Olme, olmesartan.