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A. NO711 (GAT-1 antagonist, 10 μM) (dashed lines) caused a small increase in decay time of evoked GABA responses from iMSNs to GPe neurons in both WT and R6/2 mice. B. NO711 bath application caused no change in amplitude of responses in either WT or R6/2 neurons. However, it caused significant increase in decay time in both WT and R6/2 neurons. C. The percent change of decay time of WT neurons was not significantly different from R6/2 neurons after application of NO711.
