Table 4.
Week 10 change from baseline TNF- α concentrations (pg/mL) in cell culture supernatant of dogs consuming a SCFP-supplemented or control diet
| Agonist1 | Δ Control | Δ SCFP | SEM | P-value |
|---|---|---|---|---|
| Control, pg/mL | –116.72 | –342.11 | 92.02 | 0.0957 |
| LPS (TLR4), pg/mL | 525.98 | 276.48 | 167.47 | 0.3011 |
| Zymosan (TLR2), pg/mL | 25.20 | 301.50 | 666.41 | 0.7716 |
| Poly I:C (TLR3), pg/mL | 545.55 | 132.56 | 172.15 | 0.1007 |
| Resiquimod (TLR 7/8), pg/mL | 2515.40 | 1505.74 | 1078.27 | 0.5169 |
LPS mimics a bacterial challenge, zymosan mimics a yeast challenge, and poly I:C and resiquimod mimics a viral challenge.