Table 3.
Diagnostic performance of single-photon emission computed tomography, positron emission tomography, and magnetic resonance imaging for the detection of coronary artery disease when referenced by a fractional flow reserve threshold of <0.75 on a per-patient level
| % (95% CI) | |||
|---|---|---|---|
| SPECT | PET | MRI | |
| Sensitivity | 76 (66–84) | 92 (85–97) | 77 (67–86) |
| Specificity | 62 (52–72) | 65 (54–74) | 66 (55–75) |
| PPV | 67 (60–73) | 73 (66–78) | 68 (61–75) |
| NPV | 73 (64–80) | 90 (81–95) | 75 (66–82) |
| Accuracy | 69 (62–76) | 79 (72–84) | 71 (64–78) |
| AUC | 0.73 (0.66–0.80) | 0.88 (0.83–0.93) | 0.73 (0.66–0.80) |
AUC, area under the receiver operating characteristic curve; CI, confidence interval; MRI, magnetic resonance imaging; NPV, negative predictive value; PET, positron emission tomography; PPV, positive predictive value; and SPECT, single-photon emission computed tomography.