Figure 3.

Relationship between pre-randomization peak VO₂ and pre-randomization patient-reported and physician-assessed anginal symptoms including exercise time (A), EQ-5D-5L VAS (B), SAQ angina frequency score (C), SAQ angina physical limitation score (D), SAQ quality of life score (E) and CCS angina class (F). The shaded area represents the 95% CI for the estimate of this mean effect. Higher scores on the questionnaires indicate a better angina health status and quality of life. CCS indicates Canadian Cardiovascular Society; EQ-5D-5L indicates five level version of EuroQol 5 dimensions; QOL, quality of life; SAQ, Seattle Angina Questionnaire; VAS, visual analogue score; VO₂, oxygen uptake. P values were calculated from the regression model which was adjusted for age, weight, height, and sex.