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. 2022 Sep 1;78:102803. doi: 10.1016/j.copbio.2022.102803

Figure 4.

Figure 4

The mRNA drug-product platform process: mixing of the aqueous stream with the organic stream via a proprietary T-mixing process at fixed ratios and flow rates through a set flow path, provides self-assembly of the LNP formulation with the mRNA into nm-sized particles [36].