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. 2022 Aug 18;13:969783. doi: 10.3389/fendo.2022.969783

Table 1.

Baseline characteristic of the participants included in the analysis according to AIP quartiles.

Variables AIP P value
Q1 Q2 Q3 Q4
N 4043 4043 4043 4044
AIP, mean ± SD -0.42 ± 0.10 -0.21 ± 0.05 -0.03 ± 0.06 0.27 ± 0.18 <0.001
Female, n (%) 2094 (51.79%) 1993 (49.30%) 1877 (46.43%) 1726 (42.68%) <0.001
BMI (Kg/m2), mean ± SD 20.46 ± 1.94 21.06 ± 2.00 21.58 ± 1.97 22.43 ± 1.75 <0.001
Age, mean ± SD 42.43 ± 14.72 42.66 ± 14.83 43.57 ± 14.98 44.25 ± 15.24 <0.001
SBP (mm Hg), mean ± SD 115.64 ± 15.77 118.95 ± 16.45 122.06 ± 16.35 126.26 ± 16.43 <0.001
DBP (mm Hg), mean ± SD 69.71 ± 9.61 71.73 ± 9.95 73.39 ± 10.23 76.40 ± 10.43 <0.001
ALT(U/L), median (Q1-Q3) 14.00 (11.00-18.00) 15.00 (12.00-21.00) 17.00 (13.00-23.00) 20.00 (15.00-28.00) <0.001
AST(U/L), median (Q1-Q3) 20.00 (17.00-24.00) 21.00 (18.00-25.00) 21.00 (18.00-25.00) 23.00 (20.00-27.00) <0.001
ALP(U/L), mean ± SD 64.98 ± 20.71 70.39 ± 25.11 74.21 ± 23.67 77.90 ± 21.21 <0.001
GGT(U/L), median (Q1-Q3) 17.00 (14.00-22.00) 19.00 (15.00-26.00) 22.00 (17.00-32.00) 29.00 (21.00-44.50) <0.001
CR (umol/L), median (Q1-Q3) 69.00 (61.00-79.00) 75.00 (63.00-88.00) 79.00 (66.00-93.00) 84.00 (71.00-96.00) <0.001
UA (umol/L), median (Q1-Q3) 227.00 (189.00-276.00) 250.00 (205.00-310.00) 285.00 (232.00-342.00) 325.00 (267.00-384.00) <0.001
TC (mmol/L), mean ± SD 4.57 ± 0.74 4.56 ± 0.72 4.62 ± 0.72 4.75 ± 0.78 <0.001
TG (mmol/L), median (Q1-Q3) 0.68 (0.58-0.78) 0.94 (0.83-1.07) 1.24 (1.09-1.42) 1.98 (1.63-2.53) <0.001
HDL-C (mmol/L), mean ± SD 1.81 ± 0.33 1.54 ± 0.28 1.36 ± 0.25 1.14 ± 0.21 <0.001
LDL-C (mmol/L), mean ± SD 2.11 ± 0.46 2.23 ± 0.46 2.34 ± 0.45 2.37 ± 0.45 <0.001
Fasting glucose (mmol/L), mean ± SD 4.99 ± 0.63 5.10 ± 0.73 5.17 ± 0.78 5.32 ± 0.92 <0.001
NAFLD 117 (2.89%) 315 (7.79%) 550 (13.60%) 1340 (33.14%) <0.001

AIP, atherogenic index of plasma; BMI, body mass index (BMI);SBP, systolic blood pressure; DBP, diastolic blood pressure; ALP, alkaline phosphatase; GGT, gamma glutamyl transferase; ALT, alanine aminotransferase; AST, aspartate aminotransferase; CR, serum creatinine; UA, uric acid; TC, total cholesterol; TG, total triglycerides; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol.