TABLE 2.
IPA analysis identifies increase of synthesis of reactive oxygen species in MYH6-Cre-BDNF–/– heart (activation z-score = 2.418; p = 6.05E-06).
| Genes | ID | Expr log ratio | Phospho false discovery | Location |
| CYP2A6 | ENSMUSG00000000547 | ↑∞ | 2.00E-01 | Cytoplasm |
| APOC2 | ENSMUSG00000002992 | ↑∞ | 1.52E-01 | Extracellular space |
| SERPINA1 | ENSMUSG00000072849 | ↑∞ | 4.78E-01 | Extracellular space |
| SERPINA3 | ENSMUSG00000021091 | ↑1.304 | 4.75E-03 | Extracellular space |
| RPL26 | ENSMUSG00000060938 | ↑6.286 | 5.03E-95 | Cytoplasm |
| LTF | ENSMUSG00000032496 | ↑3.135 | 2.34E-01 | Extracellular space |
| CCL5 | ENSMUSG00000035042 | ↑2.969 | 4.72E-01 | Extracellular space |
| S100A8 | ENSMUSG00000056054 | ↑2.748 | 1.82E-01 | Cytoplasm |
| CYP2E1 | ENSMUSG00000025479 | ↑1.893 | 1.70E-08 | Cytoplasm |
| RAC1 | ENSMUSG00000001847 | ↑1.404 | 6.32E-02 | Plasma membrane |
| ITGAM | ENSMUSG00000030786 | ↑1.227 | 4.75E-03 | Plasma membrane |
| CFB | ENSMUSG00000090231 | ↑1.044 | 1.31E-03 | Extracellular space |
| EGF | ENSMUSG00000028017 | ↑0.834 | 9.48E-02 | Extracellular space |
| CXCL14 | ENSMUSG00000021508 | ↑0.718 | 3.33E-01 | Extracellular space |
| NCF1 | ENSMUSG00000015950 | ↑0.688 | 2.77E-01 | Cytoplasm |
| MRC1 | ENSMUSG00000026712 | ↑0.610 | 1.59E-03 | Plasma membrane |
| HBB | ENSMUSG00000052305 | ↓-0.740 | 2.93E-01 | Cytoplasm |
| CAV1 | ENSMUSG00000007655 | ↓-0.872 | 1.81E-02 | Plasma membrane |
| HBA1/HBA2 | ENSMUSG00000069917 | ↓-0.944 | 4.36E-04 | Extracellular space |