Table 1. Characteristics of included clinical guidelines.

No.	Country (s)	Time	Organization	Targeted population	Title
Abbreviation: ACMG=American College of Medical Genetics and Genomics; AGNC=Association of Genetic Nurses and Counsellors; ASHG=American Society of Human Genetics; CCMG=Canadian College of Medical Geneticists; ESHG=European Society of Human Genetics; EU=European Union; HUGO=Human Genome Organization; P3G=Public Population Project in Genomics and Society; RCPA=Royal College of Pathologists of Australasia; UK=the United Kingdom; US=the United States.
1	US	2013	Presidential Commission for the Study of Bioethical Issues	Adults; children and adolescents	Anticipate and communicate. Ethical management of incidental and secondary findings in the clinical, research, and direct-to-consumer contexts (17)
2	US	2013	ACMG	Adults; children and adolescents	Points to consider for informed consent for genome/exome sequencing (18)
3	US	2013	ACMG	Adults; children and adolescents	ACMG recommendations for reporting of incidental findings in clinical exome and genome sequencing (19)
4	US	2014	ACMG	Adults; children and adolescents	ACMG policy statement: updated recommendations regarding analysis and reporting of secondary findings in clinical genome-scale sequencing (20)
5	US	2015	ASHG	Children and adolescents	Ethical, legal, and psychosocial implications of genetic testing in children and adolescents (21)
6	US	2017	ACMG	Adults; children and adolescents	ACMG Recommendations for reporting of secondary findings in clinical exome and genome sequencing, 2016 update (ACMG SF v2.0) (22)
7	Canada	2015	CCMG	Adults; children and adolescents	Position statement of the Canadian college of medical geneticists (13)
8	EU	2013	ESHG	Adults; children and adolescents	Whole-genome sequencing in health care: recommendations of the European Society of Human Genetics (23)
9	EU	2015	P3G, ESHG, HUGO, and PHG Foundation	Children and adolescents	A statement on the continued importance of targeted approaches in newborn screening programmes (24)
10	UK	2014	AGNC	Adults; children and adolescents	Position statement on opportunistic genomic screening (25)
11	UK	2014	PHG Foundation	Adults	Realising genomics in clinical practice (26)
12	Germany	2013	German Ethics Council	Adults	The future of genetic diagnosis: from research to clinical practice (27)
13	Australia	2014	RCPA	Adults	Implementation of massively parallel sequencing in diagnostic medical genetic testing (28)