Table III.
Association between maternal PCOS and childhood morbidity stratified by child sex.
| Hazard ratioa (95% CI) |
||
|---|---|---|
| Boys (n = 532 876) | Girls (n = 505 499) | |
| Type of hospitalization | ||
| Any | 1.31 (1.24–1.39) | 1.34 (1.26–1.43) |
| Infection | 1.31 (1.23–1.38) | 1.32 (1.24–1.41) |
| Allergy | 1.52 (1.32–1.76) | 1.38 (1.13–1.68) |
| Cancer | 0.91 (0.38–2.20) | 1.46 (0.69–3.08) |
| Physiological system | ||
| Respiratory | 1.30 (1.20–1.40) | 1.34 (1.22–1.48) |
| Cardiovascular | 1.39 (0.97–1.99) | 1.21 (0.77–1.88) |
| Metabolic | 1.76 (1.19–2.62) | 1.37 (0.82–2.28) |
| Gastrointestinal | 1.74 (1.51–2.01) | 1.68 (1.43–1.99) |
| Urinary | 1.57 (1.27–1.93) | 1.31 (1.05–1.62) |
| Genital | 1.36 (0.99–1.88) | – |
| Musculoskeletal | 0.46 (0.15–1.42) | 1.24 (0.62–2.49) |
| Central nervous system | 1.70 (1.36–2.12) | 1.79 (1.39–2.32) |
| Ophthalmologic | 1.49 (1.25–1.78) | 1.42 (1.16–1.73) |
| Otologic | 1.31 (1.22–1.42) | 1.37 (1.25–1.50) |
| Mental and behavioral | 1.73 (1.41–2.12) | 1.58 (1.20–2.10) |
a
Hazard ratio for PCOS relative to no exposure, adjusted for maternal age, parity, ART, maternal comorbidity, substance use disorder, socioeconomic deprivation and year of birth.
PCOS, polycystic ovary syndrome.