Table II.
Baseline characteristics of women in menopausal hormone therapy (MHT) users and MHT non-users.
| MHT users | MHT non-users | Chi-squared value† | |
|---|---|---|---|
| (n = 86 980) | (n = 91 024) | ||
| Year of birth | |||
| <1940 | 3845 (4.4%) | 3669 (4.0%) | χ2 = 6892.8, df = 3 |
| 1940–1949 | 56 788 (65.3%) | 42 389 (46.6%) | |
| 1950–1959 | 23 820 (27.4%) | 40 099 (44.1%) | |
| ≥1960 | 2527 (2.9%) | 4867 (5.4%) | |
| Race/ethnicity | |||
| Caucasian | 84 715 (97.4%) | 86 095 (94.6%) | χ2 = 962.9, df = 3 |
| Asian | 987 (1.1%) | 2263 (2.5%) | |
| Black | 751 (0.9%) | 1900 (2.1%) | |
| Others | 527 (0.6%) | 766 (0.8%) | |
| BMI (kg/m2) | |||
| Underweight, <18.5 | 495 (0.6%) | 781 (0.9%) | χ2 = 219.0, df = 3 |
| Normal, 18.5–24.9 | 30 942 (35.7%) | 34 718 (38.3%) | |
| Overweight, 25.0–29.9 | 34 346 (39.6%) | 33 456 (36.9%) | |
| Obese, ≥30 | 20 853 (24.1%) | 21 663 (23.9%) | |
| Smoking status | |||
| Never | 46 620 (53.8%) | 56 583 (62.4%) | χ2 = 1342.7, df = 2 |
| Past | 32 176 (37.1%) | 27 131 (29.9%) | |
| Present | 7838 (9.1%) | 7015 (7.7%) | |
| Years of education | |||
| ≤10 years | 48 603 (56.1%) | 45 368 (50.0%) | χ2 = 653.5, df = 2 |
| 11–12 years | 9475 (10.9%) | 11 252 (12.4%) | |
| >12 years | 28 573 (33.0%) | 34 062 (37.6%) | |
| Age at menarche | |||
| ≤11 | 18 492 (21.7%) | 17 640 (19.9%) | χ2 = 115.8, df = 4 |
| 12 | 15 982 (18.7%) | 17 127 (19.3%) | |
| 13 | 19 876 (23.3%) | 21 948 (24.7%) | |
| 14 | 16 662 (19.5%) | 17 537 (19.7%) | |
| ≥15 | 14 280 (16.7%) | 14 585 (16.4%) | |
| Parity | |||
| 0 | 13 102 (15.1%) | 16 187 (17.8%) | χ2 = 241.8, df = 3 |
| 1 | 11 100 (12.8%) | 11 333 (12.5%) | |
| 2 | 40 324 (46.4%) | 40 565 (44.6%) | |
| ≥3 | 22 405 (25.8%) | 22 877 (25.2%) | |
| Family history of CVD # | |||
| Yes | 53 802 (63.0%) | 53 454 (59.7%) | χ2 = 201.7, df = 1 |
| No | 31 569 (37.0%) | 36 065 (40.3%) | |
| Family history of breast cancer | |||
| Yes | 6050 (7.2%) | 7731 (8.7%) | χ2 = 144.2, df = 1 |
| No | 78 498 (92.8%) | 80 953 (91.3%) | |
| Family history of lung cancer | |||
| Yes | 11 287 (13.2%) | 10 762 (12.0%) | χ2 = 57.0, df = 1 |
| No | 74 084 (86.8%) | 78 757 (88.0%) | |
| Family history of colorectal cancer | |||
| Yes | 9002 (10.5%) | 8757 (9.8%) | χ2 = 27.8, df = 1 |
| No | 76 369 (89.5%) | 80 762 (90.2%) |
†
All P-values were <0.001.
#
Cardiovascular diseases, including coronary heart disease and stroke.