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. 2022 Jun 30;37(9):2063–2074. doi: 10.1093/humrep/deac147

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© The Author(s) 2022. Published by Oxford University Press on behalf of European Society of Human Reproduction and Embryology.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (https://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Figure 3. — Scatter plots of paternal age at blood sampling against paternal biomarkers of aging. (A) DNAm-estimated ‘Pace of Aging’ (referred to as DunedinPoAm) by Belsky et al. (2020), (B) PhenoAge by Levine et al. (2018), (C) DNAm-estimated telomere length (DNAmTL) by Lu et al. (2019), (D) DNAmAge by Horvath (2013) and (E) DNAmAge by Hannum et al. (2013). The red dots refer to the fathers with 95% percentile of DunedinPoAm, while the blue dots refer to the fathers with 5% percentile of DunedimPoAm. The dotted line indicates the linear regression of each biomarker of aging on paternal age at blood sampling. DNAm, DNA methylation; PhenoAge, DNAm-estimated phenotypic age; DNAmTL, DNAm-estimated telomere length; DNAmAge, DNA methylation age.