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. 2022 Aug 18;13:924062. doi: 10.3389/fpsyt.2022.924062

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Copyright © 2022 Yang, Yang, Mao and Li.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Comparisons of cg25427638 methylation, CYP2B6 expression, and smoker percentage between subjects with zero copies of rs3745277 minor allele and those with either one or two copies in AAs or EAs, respectively. The four boxplots indicate methylation at cg25427638 (A) and expression for CYP2B6 (B) for subjects with 0 or 1/2 copies of rs3745277 minor allele (A) in the AA (left) or EA (right) ethnic group. Student’s t-test results are included. The barplots in (C) illustrate smoker and non-smoker percentages for each genotype group in AAs or EAs. Fisher’s exact test was performed to obtain the p-values for this panel. P-values < 0.05 are considered significant.