Table 1.
Percent phenotypic variance explained by gut microbial alpha and beta diversity measures in each of the experimental diet.
| Faith's PD | Observed ASV | Shannon | Weighted UniFrac PC1 | Unweighted UniFrac PC1 | Bray Curtis PC1 | |
|---|---|---|---|---|---|---|
| Control | ||||||
| Body weight | 27.4% | 26.1% | 4.7% | 6.5% | 6.6% | 15.7% |
| Fat mass | 13.8% | 16.7% | 26.4% | 0.1% | 1.1% | 1.3% |
| Lean mass | 20.8% | 19.9% | 1.1% | 7.0% | 7.6% | 20.9% |
| Body fat percentage | 2.9% | 5.6% | 21.4% | 2.2% | 1.5% | 11.4% |
| Fasting glucose | 0.2% | 1.5% | 4.2% | 3.3% | 0.0% | 3.0% |
| Insulin | 0.4% | 0.3% | 2.1% | 15.7% | 0.2% | 19.7% |
| GTT | 15.7% | 11.3% | 0.1% | 2.0% | 0.6% | 6.8% |
| Japanese | ||||||
| Body weight | 0.5% | 0.8% | 7.2% | 0.7% | 0.2% | 1.6% |
| Fat mass | 11.4% | 2.2% | 1.2% | 2.9% | 6.2% | 2.8% |
| Lean mass | 1.9% | 5.5% | 5.3% | 2.0% | 4.9% | 0.2% |
| Body fat percentage | 12.8% | 4.4% | 0.3% | 4.8% | 14.4% | 4.2% |
| Fasting glucose | 0.0% | 0.2% | 0.4% | 2.1% | 10.5% | 11.1% |
| Insulin | 0.1% | 0.7% | 4.4% | 2.1% | 22.3% | 1.9% |
| GTT | 0.4% | 4.2% | 6.4% | 5.5% | 23.4% | 9.9% |
| Ketogenic | ||||||
| Body weight | 2.3% | 0.8% | 7.2% | 2.1% | 14.4% | 23.1% |
| Fat mass | 6.6% | 3.5% | 0.7% | 14.1% | 0.5% | 1.0% |
| Lean mass | 0.8% | 0.1% | 5.4% | 0.0% | 34.0% | 20.2% |
| Body fat percentage | 3.0% | 2.3% | 0.1% | 11.1% | 8.8% | 1.0% |
| Fasting glucose | 2.6% | 1.2% | 11.6% | 16.8% | 0.4% | 31.3% |
| Insulin | 17.0% | 16.6% | 0.3% | 0.1% | 1.8% | 13.7% |
| GTT | 1.7% | 0.4% | 12.0% | 11.8% | 0.3% | 27.8% |
| Mediterranean | ||||||
| Body weight | 1.7% | 2.2% | 11.4% | 2.2% | 3.9% | 0.8% |
| Fat mass | 0.3% | 0.6% | 13.4% | 0.0% | 0.9% | 3.3% |
| Lean mass | 2.8% | 2.9% | 9.5% | 4.8% | 14.7% | 5.3% |
| Body fat percentage | 0.1% | 0.1% | 7.0% | 0.7% | 6.6% | 7.7% |
| Fasting glucose | 1.2% | 2.9% | 22.1% | 12.4% | 18.3% | 23.2% |
| Insulin | 9.5% | 4.4% | 1.4% | 3.8% | 11.3% | 31.3% |
| GTT | 3.5% | 0.3% | 12.0% | 5.5% | 0.4% | 0.1% |
| Western | ||||||
| Body weight | 6.5% | 10.7% | 0.6% | 17.7% | 5.5% | 0.6% |
| Fat mass | 2.9% | 1.7% | 19.3% | 3.7% | 1.7% | 11.3% |
| Lean mass | 27.8% | 33.3% | 18.5% | 24.2% | 24.4% | 14.4% |
| Body fat percentage | 23.5% | 21.1% | 49.5% | 2.7% | 18.0% | 42.1% |
| Fasting glucose | 36.1% | 38.5% | 7.2% | 31.5% | 42.9% | 10.8% |
| Insulin | 0.5% | 2.5% | 0.2% | 40.0% | 0.2% | 0.0% |
| GTT | 36.9% | 46.7% | 18.1% | 28.3% | 25.8% | 11.4% |
Percent variance explained was calculated from the correlation coefficient.