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. 2022 Aug 18;9:896348. doi: 10.3389/fnut.2022.896348

Table 2.

Percent phenotypic variance explained by gut microbial alpha and beta diversity measures in each of the mouse strains.

Faith's PD Observed ASV Shannon Weighted UniFrac PC1 Unweighted UniFrac PC1 Bray Curtis PC1
A/J
Body weight 3.3% 1.0% 0.9% 4.5% 0.8% 0.1%
Fat mass 6.5% 6.5% 0.2% 21.7% 3.0% 0.1%
Lean mass 0.0% 1.0% 3.7% 0.5% 8.1% 0.7%
Body fat percentage 9.3% 11.9% 3.6% 24.3% 9.2% 1.6%
Fasting glucose 1.0% 4.1% 14.9% 8.7% 27.2% 10.1%
Insulin 0.0% 0.5% 27.3% 0.6% 28.6% 22.7%
GTT 5.6% 4.6% 5.3% 0.0% 6.2% 4.4%
C57BL/6J
Body weight 23.4% 16.1% 14.1% 8.5% 16.0% 4.8%
Fat mass 24.3% 18.4% 14.7% 16.0% 13.7% 6.6%
Lean mass 15.2% 10.5% 8.7% 0.5% 8.6% 2.2%
Body fat percentage 18.8% 14.3% 10.5% 18.1% 9.4% 30.0%
Fasting glucose 39.3% 34.7% 30.2% 11.4% 32.1% 15.7%
Insulin 40.1% 32.7% 42.0% 25.7% 34.9% 25.4%
GTT 2.0% 0.1% 5.0% 0.6% 3.8% 9.9%
FVB/NJ
Body weight 2.5% 0.1% 1.3% 3.8% 3.6% 1.1%
Fat mass 10.1% 3.9% 3.3% 2.3% 0.6% 2.0%
Lean mass 0.1% 3.8% 0.1% 9.8% 6.4% 5.7%
Body fat percentage 13.3% 9.3% 5.9% 7.5% 0.1% 7.3%
Fasting glucose 2.0% 7.9% 0.5% 12.4% 4.6% 14.1%
Insulin 1.6% 4.8% 2.6% 47.1% 35.9% 21.4%
GTT 1.1% 7.7% 1.3% 3.8% 0.9% 4.3%
NOD/ShiLtJ
Body weight 4.9% 7.6% 11.4% 4.8% 12.5% 0.1%
Fat mass 3.3% 3.0% 4.2% 4.4% 13.6% 0.4%
Lean mass 6.5% 12.0% 16.1% 2.5% 2.3% 2.4%
Body fat percentage 0.2% 0.0% 0.0% 3.1% 11.8% 2.0%
Fasting glucose 1.1% 4.0% 0.0% 4.8% 17.9% 4.0%
Insulin 0.0% 0.0% 0.0% 0.0% 0.0% 0.0%
GTT 1.7% 0.6% 13.6% 5.6% 26.4% 3.5%

Percent variance explained was calculated from the correlation coefficient.