. 2022 Aug 10;8(8):e10160. doi: 10.1016/j.heliyon.2022.e10160

Table 3.

Statistical analysis of EMT and T-type VGCCs gene expression profiles in TAN and malignant tissue in non-metastatic BC patients.

Genes	TAN N = 25	Malignant N = 25	Fold change groups (RGE metastatic/RGE non-metastatic)	Z	p- value
*E-Cadherin*
Min. – Max.	0.0–2.50	0.0–1.65	0.75	2.029^∗	0.042^∗
Median (IQR)	1.04 (0.82–1.35)	0.78 (0.72–1.10)	0.75	2.029^∗	0.042^∗
*N-Cadherin*
Min. – Max.	0.13–2.51	0.47–102.39	1.15	2.442^∗	0.015^∗
Median (IQR)	1.08 (0.56–1.30)	1.24 (1.2–2.8)	1.15	2.442^∗	0.015^∗
*Snail*
Min. – Max.	0.002–0.052	0.002–0.223	0.75	0.571	0.568
Median (IQR)	0.008 (0.004–0.010)	0.006 (0.004–0.109)	0.75	0.571	0.568
*Vimentin*
Min. – Max.	0.15–3.49	0.06–147.95	1.17	2.315^∗	0.021^∗
Median (IQR)	1.06 (0.63–2.02)	1.24 (0.9–6.3)	1.17	2.315^∗	0.021^∗
*CACNA1G*
Min. – Max.	0.0–605.09	0.0–0.98	0.42	3.632^∗	<0.001^∗
Median (IQR)	1.16 (0.85–3.07)	0.49 (0.41–0.76)	0.42	3.632^∗	<0.001^∗
*CACNA1H*
Min. – Max.	0.0–2.59	0.0–89.64	1.12	2.052^∗	0.040^∗
Median (IQR)	1.22 (0.79–1.68)	1.37 (1.2–3.7)	1.12	2.052^∗	0.040^∗
*CACNA1I*
Min. – Max.	0.01–3.43	0.18–58.51	0.92	0.600	0.549
Median (IQR)	0.92 (0.42–1.50)	0.85 (0.28–0.79)	0.92	0.600	0.549

Z: Wilcoxon signed ranks test.

RGE = Relative gene expression.

^∗

= significant difference.