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. 2022 Jul 25;41(17):e109205. doi: 10.15252/embj.2021109205

Figure EV1. Ligation of rBM in 2D versus 3D alters cellular gene expression profiles.

Figure EV1

  • A
    Heatmap of microarray analysis of gene expression in HMT‐3522 S‐1 MECs cultured either as a 2D monolayer or as spheroids. The top 200 differentially expressed genes are shown (n = 3 independent biological replicates).
  • B
    Heatmap of RNA‐seq experiment from MCF10A MECs ligated with rBM in 2D and 3D at 12 h post‐plating. The top 200 genes differentially expressed between the 2D and 3D rBM conditions are shown (n = 3 independent biological replicates).