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. 2022 Aug 18;12:956940. doi: 10.3389/fonc.2022.956940

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Copyright © 2022 Iazzolino, Mendibil, Arnaiz, Ruiz-de-Angulo, Azkargorta, Uribe, Khatami, Elortza, Olalde, Gomez-Vallejo, Llop and Abarrategi

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Proteomic study shows distinctive ECM on decellularized TNBC xenograft samples. (A) Principal component analysis (PCA). Matrigel control samples are plotted separately from all tumor xenograft samples. Tumor xenograft samples come out splinted into two groups, with the two TNBC xenograft-derived samples separated from the rest of the samples. (B) Heat map representation of the 50 more discriminant proteins obtained by partial least squares discriminant analysis (PLS-DA). (C) GO analysis of the 50 more discriminant proteins. Note: cell line number codes are provided in Table 1 . The same tumor color codes are used in all panels of the figure.