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. 2022 May 18;28(5):733–746. doi: 10.1093/humupd/dmac021

Figure 3.

Figure 3.

Forest plots for live birth and multiple pregnancy. (a–c) Live birth: (a) comparing gonadotrophins and CC; (b) comparing letrozole and CC; (c) comparing gonadotrophins and letrozole. (d–f) Multiple pregnancy: (d) comparing gonadotrophins and CC. (e) Comparing letrozole and CC. (f) Comparing gonadotrophins and letrozole. In each forest plot, the study level estimate was based on individual patient data (IPD) of each individual study and the summary estimate was based on a one-stage IPD meta-analysis (IPD-MA). In (a), Ecochard (2000) did not report live birth and therefore was not included in the IPD-MA. In (d), Ecochard (2000) did not report multiple pregnancy and therefore was not included in the IPD-MA. Note that study level estimates were not shown for two other studies (Peeraer, 2015; Naidu, 2020), due to the presence of 0 events in one group (Peeraer, 2015) or 0 events in both groups (Naidu, 2020), but the one-stage IPD-MA for multiple pregnancy included these two studies. CC, clomiphene citrate; RR, relative risk.