Table IV.
Meta-analyses of treatment-covariate interactions on live birth.
| Comparison | Baseline covariate | Number of RCTs | Number of participants | Risk ratio (RR) | 95% CI | I 2 |
|---|---|---|---|---|---|---|
| Gn vs CC | Age | 5 | 1920 | 0.94 | 0.85–1.05 | 61% |
| BMI | 4 | 1808 | 1.03 | 0.95–1.11 | 40% | |
| Type of infertility (primary vs secondary) | 3 | 1589 | 0.86 | 0.58–1.26 | 0% | |
|
| ||||||
| Letrozole vs CC | Age | 1 | 599 | 1.03 | 0.96–1.10 | |
| BMI | 1 | 599 | 1.02 | 0.98–1.08 | ||
| Type of infertility (primary vs secondary) | 1 | 599 | 1.33 | 0.70–2.54 | ||
|
| ||||||
| Gn vs Letrozole | Age | 1 | 600 | 1.02 | 0.95–1.09 | |
| BMI | 1 | 600 | 0.99 | 0.94–1.03 | ||
| Type of infertility (primary vs secondary) | 1 | 600 | 0.60 | 0.33–1.09 | ||
Gn, gonadotrophins; CC, clomiphene citrate; RCT, randomized controlled trial.