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. 2022 Aug 18;13:978747. doi: 10.3389/fendo.2022.978747

Table 2.

Association of cardiometabolic risk factors and laboratory values in 2014 with RTL at follow up in 2019 and ΔRTL.

Cardiometabolic risk factors and laboratory values in 2014 All sample N=196 RTL at follow-up ΔRTL
Correlation (r) mean±SD p-value Correlation (r) mean±SD p-value
Diabetes
Definite Diabetes 0.09 0.30
 No 163 (83.2) 1.22±1.06 -0.27±1.12
 Yes 33 (16.8) 0.89±0.53 -0.49±1.08
Self-reported diabetes or hyperglycemia diagnosis 0.16 0.88
 No 169 (86.2) 1.21±1.05 -0.30±1.15
 Yes 27 (13.8) 0.93±0.54 -0.33±0.94
Diabetes treatment 0.24 0.84
 No 169 (86.2) 1.20±1.05 -0.31±1.14
 Yes 27 (13.8) 0.95±0.53 -0.27±0.95
Fasting serum glucose (mg/dL) 0.37 0.138
 <100 – normal 90 (45.9) 1.10±0.55 -0.44±0.96
 ≥100 – abnormal 106 (54.1) 1.22±1.26 -0.20±1.23
Insulin (μIU/mL), Mean (±SD) 28.95±11.62 -0.063 0.415 -0.046 0.558
HbA1c (%), Mean (±SD) 5.9±1.2 -0.098 0.170 -0.021 0.768
C peptide (ng/dL), Mean (±SD) 3.18±1.37 -0.146 0.044 -0.154 0.033
Hypertension (HTN)
Definite HTN
 No 127 (64.8) 1.20±1.12 0.51 -0.36±1.20 0.40
 Yes 69 (35.2) 1.10±0.71 -0.22±0.95
Self-reported HTN diagnosis 0.26 0.94
 No 159 (81.1) 1.20±1.07 -0.31±1.20
 Yes 37 (18.9) 1.00±0.57 -0.30±1.26
HTN treatment 0.17 0.79
 No 161 (82.1) 1.21±1.07 -0.30±1.14
 Yes 35 (17.9) 0.96±0.53 -0.35±1.02
Systolic Blood Pressure (mm/Hg), Mean (±SD) 121.97±19.05 -0.120 0.093 0.007 0.921
Diastolic Blood Pressure (mm/Hg), Mean (±SD) 75.73±10.28 0.008 0.908 0.062 0.388
Dyslipidemia
Self-reported dyslipidemia diagnosis 0.83
 No 146 (74.5) 1.17±1.09 -0.36±1.20 0.27
 Yes 50 (25.5) 1.14±0.65 -0.16±0.80
Dyslipidemia treatment 0.11 0.90
 No 156 (79.6) 1.22±1.09 -0.30±1.18
 Yes 40 (20.4) 0.94±0.08 -0.33±0.85
HDL (mg/dL), Mean (±SD) 49.38±13.80 -0.052 0.465 -0.058 0.420
LDL (mg/dL), Mean (±SD) 111.64±36.89 0.040 0.574 0.098 0.174
Triglycerides (mg/dL), Mean (±SD) 142.18±72.41 0.022 0.763 0.065 0.369
Metabolic syndrome
Metabolic Syndrome
 No 86 (43.9) 1.13±0.60 0.62 -0.39±1.04 0.35
 Yes 110 (56.1) 1.20±1.23 -0.24±1.17
Atherosclerotic vascular disease (ASCVD) risk
ASCVD 10 yrs risk (%), Mean (±SD) 7.79±7.45 -0.133 0.154 -0.075 0.426
Other
CRP (mg/L), Mean (±SD) 11.77±7.27 -0.006 0.934 -0.033 0.649
Cortisol (μg/dL), Mean (±SD) 18.47±12.27 -0.052 0.484 0.058 0.432

Bolded P-values are statistically significant as they are less or equal to 0.05.