Summary of PK and total LIF concentrations by cohort. (A) Geometric mean ± SD of serum MSC-1 concentration–time profiles and (B) mean ± SD of serum total LIF concentration–time profiles following Q3W i.v. infusion of MSC-1 in patients with advanced solid tumors.
i.v., intravenous; LIF, leukemia inhibitory factor; PK, pharmacokinetics; Q3W, once every 3 weeks; SD, standard deviation; tLIF, total LIF.