Table 4.

DFAR scores’ prediction by SZ PRS, BD PRS, and MDD PRS

Model	SZ PRS
	B	SE	95% CI	P value
DFAR total	−0.7	0.9	−2.5 to 1.1	.466
DFAR neutral	2.6	1.4	−0.1 to 5.4	.060
DFAR happy	0.3	1.1	−1.8 to 2.4	.784
DFAR fear	−2.4	1.6	−5.6 to 0.8	.136
DFAR anger	−3.5	1.7	−6.9 to −0.2	.040
	BD PRS
DFAR total	−0.6	0.5	−1.7 to 0.4	.220
DFAR neutral	−0.8	0.8	−2.4 to 0.7	.297
DFAR happy	−0.5	0.6	−1.8 to 0.7	.383
DFAR fear	−0.6	0.9	−2.4 to 1.2	.525
DFAR anger	−0.7	0.9	−2.7 to 1.2	.459
	MDD PRS
DFAR total	0.2	0.7	−1.3 to 1.6	.793
DFAR neutral	2.7	1.1	0.5 to 4.9	.017
DFAR happy	−0.3	0.9	−1.9 to 1.4	.743
DFAR fear	−1.2	1.3	−3.8 to 1.3	.347

Note: Linear regression models adjusted for case/control status, age, sex, BFRT, IQ, and 20 PCs.

SZ, schizophrenia; BD, bipolar disorder; MDD, major depression disorder; PRS, polygenic risk score; DFAR, degraded facial affect recognition.