Table 1.
Schizophrenia (mean ± SD) n = 31 |
Healthy volunteer (mean ± SD) N = 21 |
t/χ 2 | P | |
---|---|---|---|---|
Age | 31.87 ± 7.67 | 25.33 ± 3.86 | 3.60 | 0.001 |
Education | 15.06 ± 2.17 | 16.90 ± 2.68 | 2.72 | 0.009 |
Global Assessment of functioning | 60.32 ± 15.91 | 93.81 ± 2.48 | 9.54 | <0.001 |
PANSS -positive | 11.65 ± 5.43 | - | - | - |
PANSS-negative | 12.39 ± 5.54 | - | - | - |
PANSS- general psychopathology | 26.03 ± 4.92 | - | - | - |
PANSS - total | 49.77 ± 12.37 | - | - | - |
SANS | 24.06 ± 16.97 | - | - | - |
Clinical Global Impression | 3.48 ± 1.12 | - | - | - |
CDSS | 2.03 ± 1.66 | - | - | - |
Age at onset of psychosis in years | 21.57 ± 4.58 | - | - | - |
Duration of illness in years | 8.8 5 ± 5.75 | - | - | - |
OXTR polymorphism (G/G:A/G) | 26:5 | 18:3 | 0.03 | 1.00 |
t – Independent t-test; χ2 – Chi-square test; PANSS – Positive and negative syndrome scale; SANS – Scale for assessment of negative symptoms; OXTR – Oxytocin receptor polymorphism (rs2254298)