Table 1.

Prions of S. cerevisiae and Podospora anserina.

Prion	Protein	Normal Function	Prion Phenotype	Ref.
[URE3]	Ure2p	Nitrogen regulation	Inappropriate derepression of nitrogen catabolism genes; slow growth	[4]
[PSI+]	Sup35p	Translation termination	Readthrough of translation stop codons	[4]
[PIN+]	Rnq1p	Unknown	Rare cross – seeding of [PSI+] or other prions	[79]
[SWI+]	Swi1p	Chromatin remodeling	Inability to utilize non-fermentable carbon source and slow growth	[80]
[OCT+]	Cyc8p	Transcription repression	Derepressed transcription; flocculence	[81]
[MOT+]	Mot3p	Repressor of genes for anaerobic growth	Inappropriate derepression of anaerobic growth genes	[82]
[ISP+]	Sfp1p	Transcription factor	Decreased translation read through	[83]
[MOD+]	Mod5p	tRNA isopentenyl - transferase	Slow growth; resistance to azole anti-fungal drugs	[84]
[Het-s]	HET-s	Heterokaryon incompatibility	Heterokaryon incompatibility in Podospora anserina (a functional prion)	[63]
[BETA]	Prb1p	Vacuolar protease B	normal sporulation, survival in stationary phase (a functional prion)	[85]