Table 3.
Patient characteristics of physiological parameters at MRI examination
| AKI (N = 10) | NO AKI (N = 9) | |
|---|---|---|
| Current Plasma-Creatinine, µmol/l [IQR] | 104 [101–114] | 67 [64–77] |
| Current eGFR (Creatinine), ml/min [IQR] | 56 [49–59] | 87 [78–90] |
| Current KDIGO Creatinine AKI Stage | 1 [1–1] | |
| Last recorded hourly urine output, ml/kg [IQR] | 0.9 [0.3–1.7] | 1 [0.8–1.7] |
| Last recorded hourly urine output, ml [IQR] | 65 [35–131] | 110 [80–150] |
| Furosemide within 12 h before MRI scan, mg [IQR] | 8 [1–10] | 0 [0–0] |
| Time since latest furosemide, h [IQR] | 7 [5–20] | 28 [17–36] |
| Any furosemide within 3 h before MRI scan, n (%) | 2 (20%) | 1 (11%) |
| Net fluid intake at examination day, ml [IQR] | 318 [− 15 to 629] | 184 [-16–429] |
| SOFA score, points [IQR] | 7 [7, 8] | 6 [4–6] |
| Days of symptomatic COVID-19, n [IQR] | 17 [14–19] | 12 [11–14] |
| Days in ICU at examination, n [IQR] | 8 [4–8] | 3 [2–5] |
| Plasma-CRP, mg/l [IQR] | 98 [71–140] | 115 [64–186] |
| Days since start of invasive ventilation, n [IQR] | 4 [2–5] | 2 [2, 3] |
| Arterial oxygen saturation | 96% [93–97] | 95% [95–98] |
| Arterial pO2, kPa [IQR] | 10 [10, 11] | 10 [10–12] |
| Arterial pCO2, kPa [IQR] | 6.3 [5.7–6.6] | 5.5 [5.2–6] |
| Arterial pH, [IQR] | 7.39 [7.37–7.41] | 7.42 [7.4–7.44] |
| P/f-ratio, kPa [IQR] | 21 [20–27] | 26 [25–33] |
| PEEP, cmH2O [IQR] | 14 [13–15] | 10 [9–12] |
| Mean arterial pressure, mmHg [IQR] | 80 [79–85] | 81 [80–98] |
| Sinus rhythm, n (%) | 10 (100%) | 8 (89%) |
| Blood hemoglobin, g/dl [IQR] | 11.5 [11.3–12.3] | 12.8 [11.4–12.9] |
| Central venous saturation, [IQR] | 73% [72–77] | 67% [65–74] |
| Vasoactive drug, n (%) | 8 (80%) | 4 (44%) |
| Noradrenaline dose, µg/kg/min [IQR] | 0.05 [0.01–0.07] | 0 [0–0.03] |
| Plasma-lactate, mmol/l [IQR] | 1.4 [1–1.9] | 1.5 [1.3–1.6] |
| Plasma-NT-proBNP, ng/l [IQR] | 201 [131–633] | 373 [236–491] |
Patient characteristics of physiological parameters on the day of the MRI examination in the 19 patients included in the study who were treated in ICU for respiratory failure due to COVID-19
IQR interquartile range, eGFR estimated glomerular filtration rate, SOFA Sequential Organ Failure Assessment, CRP C-reactive protein, P/f PaO2/FiO2, PEEP positive end-expiratory pressure, NT-proBNP N-terminal pro-brain natriuretic peptide