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. 2022 Sep 1;26:262. doi: 10.1186/s13054-022-04132-8

Table 4.

Additional results of renal multiparametric MRI

AKI n NO AKI n Healthy volunteers n
Perfusion
Global perfusion (ml/100 g/min) 168 [142–216] 10 202 [174–235] 9 220 [174–242] 12
Regional perfusion ratio (cortex/medulla) 2.4 [2.2–3.3] 10 2.2 [1.7–3.4] 7
Resistance index* 0.90 [0.82–0.93] 10 0.79 [0.75–0.86] 8
Structure and regional water diffusion
Total kidney volume (ml) 356 [331–437] 10 390 [359–447] 9 403 [345–430] 12
T1 cortex (ms)† 1560 [1524–1638] 8 1522 [1497–1638] 8 1459 [1400–1525] 12
T1 medulla (ms) 1838 [1732–1872] 8 1792 [1695–1870] 8 1732 [1661–1850] 12
T2 cortex (ms) 120 [113–134] 8 124 [119–141] 8
DWI cortex ADC (× 10–3 mm2/s) 1.9 [1.9–2.1] 8 2.1 [1.9–2.1] 8
DWI medulla ADC (× 10–3 mm2/s) 1.9 [1.9–2.0] 8 2.1 [1.8–2.1] 8
DWI cortex D (× 10–3 mm2/s) 1.8 [1.7–1.9] 8 1.9 [1.7–2] 8
DWI cortex D* (× 10–3 mm2/s) 26 [23–29] 8 27 [24–28] 8
DWI cortex fp 0.13 [0.11–0.15] 8 0.13 [0.11–0.14] 8
DWI medulla D (× 10–3 mm2/s) 1.8 [1.7–1.9] 8 1.9 [1.7–2] 8
DWI medulla D* (× 10–3 mm2/s) 26 [23–17] 8 27 [26–28] 8
DWI medulla FP 0.14 [0.11–0.17] 8 0.15 [0.12–0.16] 8

Results of renal multiparametric MRI in 19 patients treated in ICU for respiratory failure due to COVID-19 with AKI or NO AKI, and 12 healthy volunteers of similar age. Data presented as median [quartile range]. Significant differences from Mann–Whitney U test between AKI and NO AKI groups are indicated by * if p < 0.05. Significant differences from one way Kruskal–Wallis ANOVA between all groups are indicated by † if p < 0.05 and ††† if p < 0.001. Valid numbers of MRI examinations are specified for each measure and group. Additional results are presented in Fig. 1

T1 longitudinal relaxation time, T2 transverse relaxation time, DWI diffusion weighted imaging, ADC apparent diffusion coefficient, D pure diffusion, D* pseudodiffusion, fp perfusion fraction