Table 4.

Hazard ratios of the indexes under investigation obtained by Cox regression analysis in non-elderly and elderly COVID-19.

Variables	HR	95% CI	p-value
WBC
Non-elderly	16.381	10.962–24.477	0.000
Elderly	7.350	5.495–9.831	0.000
All	11.210	8.831–14.299	0.000
Neutrophil
Non-elderly	15.406	10.377–22.870	0.000
Elderly	6.294	4.708–8.414	0.000
All	10.204	8.055–12.928	0.000
Lymphocyte
Non-elderly	1.620	1.145–2.291	0.001
Elderly	1.195	0.879–1.626	0.254
All	1.260	1.016–1.562	0.035
NLR
Non-elderly	4.445	3.089–6.396	0.000
Elderly	2.686	2.031–3.553	0.000
All	3.570	2.859–4.458	0.000
MLR
Non-elderly	2.058	1.455–2.910	0.024
Elderly	1.470	1.095–1.974	0.013
All	1.502	1.212–1.860	0.000
PLR
Non-elderly	1.845	1.304–2.611	0.000
Elderly	1.266	0.949–1.688	0.108
All	1.451	1.170–1.799	0.000
SIR-I
Non-elderly	5.629	3.883–8.161	0.001
Elderly	2.911	2.195–3.860	0.000
All	4.088	3.268–5.115	0.000
SII
Non-elderly	4.900	3.401–7.060	0.000
Elderly	2.823	2.132–3.739	0.000
All	3.682	2.945–4.604	0.000
dNLR
Non-elderly	1.742	1.034–2.936	0.000
Elderly	1.544	1.009–2.364	0.045
All	0.618	0.446–0.856	0.004
NLPR
Non-elderly	4.061	2.826–5.836	0.001
Elderly	2.523	1.908–3.336	0.001
All	3.327	2.667–4.151	0.000
AISI
Non-elderly	5.171	3.579–7.470	0.000
Elderly	3.307	2.486–4.399	0.000
All	4.710	3.752–5.911	0.000

AISI, aggregate index of systemic inflammation; dNLR, derived neutrophil/lymphocyte ratio; MLR, monocyte/lymphocyte ratio; NLPR, neutrophil/lymphocyte*platelet ratio; NLR, neutrophil/lymphocyte ratio; PLR, platelet/lymphocyte ratio; SII, systemic inflammation index; SIR-I, systemic inflammation response index; WBC, white blood cell.