Substrate tolerance of various alkynes over CuO/CNF nanocatalysta.
| |||
|---|---|---|---|
| Entry | Alkyne | Product | Conv.b (%) |
| 1 |
|
|
96 (93)c |
| 2 |
|
|
93 (89)c |
| 3 |
|
|
85 (79)c |
| 4 |
|
|
88 (82)c |
| 5 |
|
|
91 (85)c |
| 6 |
|
|
86 (81)c |
| 7 |
|
|
85 (83)c |
| 8 |
|
|
91 (87)c |
| 9 |
|
|
89 (84)c |
| 10 |
|
|
74 |
| 11 |
|
|
97 |
| 12 |
|
|
86 (81)c |
Experimental conditions: alkyne (1 mmol), B2Pin2 (1.2 mmol), CuO/CNF (2 mg), base (10 mol%), methanol (1 mL) under argon, 40 °C, 12 h.
Conversion determined by GC-MS.
Isolated yield.