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. 2022 Aug 19;24(4):349. doi: 10.3892/ol.2022.13469

Table II.

ABCA1 and cancer cell proliferation, invasion and metastasis.

Cancer type Cancer cell proliferation, invasion and metastasis (Refs.)
Prostate cancer High levels of cholesterol can modulate the ability of cells to migrate (49)
Breast cancer Reduced expression of ABCA1 in breast cancer appears to be associated with poor prognosis (46)
Non-small cell lung carcinoma Upregulation of the expression level of ABCA1 enhances drug resistance (45)
Lung adenocarcinoma Overexpression of ABCA1 significantly inhibits the proliferation, migration and invasion of lung adenocarcinoma cells (53)

ABC, ATP-binding cassette.