Table II.
ABCA1 and cancer cell proliferation, invasion and metastasis.
Cancer type | Cancer cell proliferation, invasion and metastasis | (Refs.) |
---|---|---|
Prostate cancer | High levels of cholesterol can modulate the ability of cells to migrate | (49) |
Breast cancer | Reduced expression of ABCA1 in breast cancer appears to be associated with poor prognosis | (46) |
Non-small cell lung carcinoma | Upregulation of the expression level of ABCA1 enhances drug resistance | (45) |
Lung adenocarcinoma | Overexpression of ABCA1 significantly inhibits the proliferation, migration and invasion of lung adenocarcinoma cells | (53) |
ABC, ATP-binding cassette.