Table 2.

Statistical differences in lipid (sub)species levels by Mann-Whitney test.

Lipid (sub)species	Discovery set					Validation set
	PreDM (All)	PreDM by IGT	PreDM by IFG	PreDM by IGT&IFG	T2DM	PreDM (All)	PreDM by IGT	PreDM by IFG	PreDM by IGT&IFG	T2DM
	n = 151	n = 78	n = 24	n = 49	n = 235	n = 150	n = 86	n = 23	n = 41	n = 234
	p	p	p	p	p	p	p	p	p	p
FA	0.003	0.001	0.776	< 0.001	< 0.001	0.017	0.069	0.442	0.011	< 0.001
Cer	0.007	0.011	0.483	0.024	< 0.001	0.023	0.147	0.891	0.001	< 0.001
HexCer	0.261	0.538	0.848	0.110	0.136	0.809	0.610	0.384	0.402	0.793
Hex2Cer	0.845	0.860	0.583	0.579	0.463	0.997	0.868	0.794	0.916	0.869
SM	0.001	0.005	0.252	0.005	< 0.001	0.001	0.049	0.022	< 0.001	< 0.001
LPC	0.941	0.767	0.801	0.675	0.721	0.621	0.973	0.593	0.089	0.695
LPC-O	0.468	0.942	0.357	0.329	0.989	0.425	0.538	0.671	0.188	0.452
LPE	0.151	0.470	0.199	0.142	0.022	0.084	0.244	0.696	0.027	0.008
PC	0.019	0.018	0.837	0.026	< 0.001	< 0.001	< 0.001	0.092	0.001	< 0.001
PC-O	0.029	0.04	0.151	0.208	0.016	0.029	0.203	0.062	0.030	0.058
PE	< 0.001	< 0.001	0.216	0.018	< 0.001	0.001	0.003	0.451	0.003	< 0.001
PE-O	0.765	0.954	0.162	0.776	0.683	0.544	0.132	0.595	0.552	0.86
PG	0.016	0.028	0.023	0.305	< 0.001	0.327	0.817	0.032	0.160	0.064
PI	0.005	0.006	0.868	0.009	< 0.001	0.416	0.171	0.524	0.518	0.019
DG	0.003	0.009	0.751	0.003	< 0.001	0.013	0.006	0.131	0.004	< 0.001
TG	0.016	0.017	0.817	0.018	< 0.001	0.023	0.010	0.188	0.015	< 0.001
TG-O	0.121	0.077	0.791	0.344	< 0.001	0.294	0.542	0.484	0.031	0.001
CE	0.110	0.064	0.404	0.103	0.019	< 0.001	0.010	0.079	< 0.001	0.002