Table 2.

Change in HDL-c in breast cancer patients on DOX treatment

Study	Sample	Chemotherapy regimen and duration	Results
[144]	N = 1054 breast cancer patients	TAC (n = 251) Cycled every 21 days for 6 cycles CEF (n = 9) Cycled every 21 days for 6 cycles AC-T (n = 134) AC cycled every 21 days for 6 cycles followed by T cycled every 21 days for 4 cycles	↓ HDL-c prechemotherapy vs. post chemotherapy
[152]	N = 12 breast cancer patients	AC-P (n = 7) AC 3 times weekly for 4 weeks followed by P once weekly for 12 weeks CEF-T (n = 5) 3 times weekly for 3 weeks followed by T 3 times weekly for 3 weeks	↓ HDL-c prechemotherapy vs. post chemotherapy

A Doxorubicin, C Cyclophosphamide, E Epirubicin, F 5-Flouracil, T Docetaxel, P Paclitaxel, vs. Versus