Table 3.
Generalized estimating equation model for the treatment effect
| Parameter | B | Standard error | 95% confidence interval | p value | |
|---|---|---|---|---|---|
| Lower | Upper | ||||
| Model 1 | |||||
| Time: before | 6.36 | 3.03 | 0.41 | 12.31 | 0.03 |
| Time: after* | Reference | – | – | – | – |
| Change in HADS_ Anxiety | 2.38 | 0.51 | 1.38 | 3.38 | < 0.01 |
| Model 2 | |||||
| Time: before | 9.20 | 2.79 | 3.72 | 14.69 | < 0.01 |
| Time: after* | Reference | – | – | – | – |
| HADS-anxiety | 0.93 | 0.63 | − 0.30 | 2.17 | 0.14 |
| HADS-depression | 2.19 | 0.67 | 0.87 | 3.51 | < 0.01 |
| Marital status: married | 12.10 | 4.53 | 3.22 | 20.98 | < 0.01 |
| Marital status: single | Reference | – | – | – | – |
| Age | − 0.21 | 0.28 | − 0.78 | 0.34 | 0.45 |
| Time from diagnosis | 1.67 | 0.70 | 0.29 | 3.05 | 0.01 |
Model 1 is adjusted for change of anxiety and model 2 is adjusted for baseline anxiety, depression, marital status, age, and time from diagnosis
HADS hospital anxiety and depression scale
*This parameter is redundant